Alzheimer’s Disease

Alzheimer’s disease is a type of brain disorder that causes problems with memory, thinking and behaviour. This is a gradually progressive condition.

  • Urgent medical attention is usually recommended by healthcare providers

  • May be dangerous or life threatening

  • Treatments can help manage condition, no known cure

  • Often requires lab test or imaging

  • Can last several years or be lifelong

  • Common for ages 60 and older

  • More common in females

  • Family history may increase likelihood

If you or someone you know is exhibiting symptoms of Alzheimer's disease, seek medical attention immediately.

Alzheimer's causes a gradual decline in memory, thinking and reasoning skills

Symptoms depend on the stage of the disease:

Early symptoms include:

  • Memory loss

  • Misplacing items

  • Forgetting the names of places and objects

  • Repeating themselves regularly, such as asking the same question several times

  • Becoming less flexible and more hesitant to try new things

Middle-stage symptoms include:

  • Increasing confusion and disorientation

  • Obsessive, repetitive or impulsive behaviour

  • Delusions (believing things that are untrue)

  • Problems with speech or language (aphasia)

  • Disturbed sleep

  • Changes in mood, such as frequent mood swings, depression and feeling increasingly anxious, frustrated or agitated

  • Difficulty in performing spatial tasks, such as judging distances

  • Agnosia

Later symptoms include:

  • Difficulty in changing position or moving around without assistance

  • Considerable weight loss – although some people eat too much and put on weight

  • Gradual loss of speech

  • Significant problems with short and long-term memory

Causes

Affected brain tissue contains:

  • Alzheimer's disease causes shrinkage (atrophy) of the posterior part of the brain.

  • Amyloid plaques (abnormal deposits of protein) that damage and destroy brain cells.

  • Neurofibrillary tangles- Brain cells require the normal structure and functioning of a protein called tau. In Alzheimer's, threads of tau protein twist into abnormal tangles inside brain cells, leading to the death of brain cells.

  • Factors known to increase the risk of developing the condition are:

  • Age -advanced age

  • Family history and genetics

  • Down syndrome

  • Head injuries

  • Past head trauma

  • Mild cognitive impairment

Prevention

Reduce your risk of cardiovascular disease. Cardiovascular disease has been linked with an increased risk of Alzheimer's disease and vascular dementia.

  • Exercise regularly

  • Engage in social activities

  • Have a healthy diet

  • Get quality sleep

  • Manage stress effectively

  • Stop smoking

  • Maintain a healthy weight-height ratio

Complications

At a later stage, complications may include:

  • Pneumonia and other infections

  • Falls and fractures

  • Bedsores

  • Malnutrition or dehydration


Sources:

https://www.msn.com/en-ph/health/condition/in-alzheimers-disease/in-Alzheimers%20Disease

Diagram showing what a healthy brain vs alzheimers brain looks like
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